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LISTERINE ANTISEPTIC : 3x greater bacteria-killing power ™ 1,†,‡ than CREST Pro-Health ® ® BACTERIAL VIABILITY STAIN OF IN VITRO BIOFILMS AFTER 60 SECOND TREATMENT WITH DIFFERENT MOUTHRINSES. 2 Viable cells are green whereas dead or damaged cells appear red or orange. NEGATIVE CONTROL (25% microorganism-free saliva in PBS) CREST ® PRO-HEALTH ™ LISTERINE ® POSITIVE CONTROL (70% EtOH) EXTEND YOUR DEEP CLEAN * WITH AN ESSENTIAL RECOMMENDATION POWERED WERED BY OUR 4 ESSENTIA SSENTIAL OI LS FO RMU L A *Rinsing with LISTERINE ® Brand Mouthwash Products does not replace a routine professional prophylaxis and is not indicated for the treatment of periodontitis or tartar removal. † In this lab model, saliva-derived biofilms were grown on saliva-coated glass slides. Biofilms were cultured for 65 hours prior to mouthrinse exposure. Biofilms were stained to enable quantifications of the live, dead cells. ‡ Non-alcohol formula. REFERENCES: 1. Pan PC, Harper S, Ricci-Nittel D, Lux R, Shi W. In-vitro evidence for efﬁcacy of antimicrobial mouthrinses. Journal of Dentistry. 2010;38(1):16-20. 2. The mode of action of LISTERINE ® Antiseptic has been shown to penetrate biofilms significantly (1 X 60 seconds) and when used as per recommended directions (2 x 30 seconds) % reduction can be as much as 3X greater than CPH. The third-party trademarks used herein are trademarks of their respective owners. COOL MINT ® LISTERINE ® Antiseptic has earned the ADA Seal of Acceptance. ©McNEIL-PPC, Inc. 2012 Use only as directed.

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Listerine